Summary: Novartis Pharmaceuticals Corporation is conducting a clinical research study for the treatment of high blood pressure.
This study evaluates the effectiveness and safety of an investigational drug in combination with an FDA approved drug for the treatment of patients with high blood pressure. The study will examine if the combination of the investigational drug and FDA approved drug lowers blood pressure as much as the FDA approved drug does alone.
Participants must meet the following criteria:
• Must be 18 years of age or older
• Must have a doctor’s diagnosis of high blood pressure
• Must have diastolic blood pressure (lower number) less than 110
Patients will be excluded from the studies for any of the following reasons:
• History of malignancy including leukemia and lymphoma (but not basal cell skin cancer) within the past 5 years
• Experienced a heart attack, stroke, or by-pass surgery in the last 12 months
• Women who are pregnant or breast-feeding
• Experienced inflammatory bowel disease within the last 12 months or had gastrointestinal surgery
• Current diagnosis of congestive heart failure
• Type 1 or Type 2 diabetes mellitus with glycosylated hemogloving (HbA1c)>9% at Visit 1.
For additional information about this study, Contact:
Irit Steiner, Study Coordinator
Richard M. Levy, MD
3580 California Street, #302
San Francisco, CA 94118
Telephone: 415-929-9405
Fax: 415-929-1307

Summary: Novartis is conducting a 10-12 week clinical research study to find out if the combination of two FDA approved study drugs will be safe and effective in treating patients for both high blood pressure and cholesterol.
This study should provide efficacy, tolerability, and safety data for the high dose of the combination of two FDA approved study drugs indicated for high blood pressure and high cholesterol. We hope to confirm that the study drugs given in combination are as safe and effective as given alone.
Participants must meet all of the following criteria:
• Be 18-75 years of age with both high blood pressure and high cholesterol
• Female patients must not be pregnant or lactating and must agree to use acceptable forms of birth control
• Must be on a stable moderate to high dose of an approved statin drug for the past 3 months (examples: Meyacor, Zocor, Prayachol, Lescol, Lipitor, Crestor)
Participants will be excluded from the studies for any of the following reasons:
• History of major gastrointestinal tract surgery or experienced inflammatory bowel disease within the last 12 months
• History of cancer including leukemia and lymphoma (excluding basal cell skin cancer) within the past 5 years
• Diabetic patients requiring insulin treatment
• Patients with congestive heart failure that requires treatment
• History of heart attack or stroke, or within the last 12 months had by-pass surgery or angioplasty
• History of severe kidney, liver, or muscular disease
For additional information about this trial, contact:
Sheryl Grant, Study Coordinator
Jacksonville Center for Clinical Research
4085 University Blvd S, Suite 1
Jacksonville, FL 32216
Telephone: 904-730-0101
Fax: 904-730-0121

Summary: A study to evaluate the effects of two FDA approved medications for high blood pressure in patients with kidney disease
This study evaluates the effects of two FDA approved medications for high blood pressure in patients with renal insufficiency to examine the safety and effectiveness of the two medications on the kidneys.
Participants in the 8-week study will be required to attend eight office visits during that time. However, participants may have to return more often to complete or repeat procedures. Each visit should not take more than an hour.
Clinical Trial Eligibility Criteria:
• History or a new diagnosis of renal impairment
• History or a new diagnosis of hypertension or newly diagnosis
Contact:
Rolanda J. Flynn, Project Coordinator
Department of Preventive Medicine at Rush
University Medical Center
1700 West VanBuren, Suite 470
Chicago, IL 60612
Telephone: 312-563-2242
Email: rflynn@rush.edu

Summary: High Blood Pressure
How’s your blood pressure? The time it takes to get your blood pressure checked might be the few minutes that could save your life.
Clinical Research Associates, Inc. is recruiting volunteers, ages 18-80, who have been diagnosed with high blood pressure to participate in a research study to determine the efficacy and safety of an investigational treatment for hypertension. Participants will receive study medications and exams, lab work, and compensation for participation.
For additional information about this study or to enroll, contact:
Recruiting Coordinator
Clinical Research Associates, Inc.
2222 State Street, Suites B & D
Nashville, TN 37203
Telephone: 615-329-2222

To find clinical trials in your area, go to: http://www.centerwatch.com/search.asp